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KMID : 0378019600030040041
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New Medical Journal
1960 Volume.3 No. 4 p.41 ~ p.45
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Liver Disease and Serum Transaminase
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Abstract
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The increase of serum transaminase at fresh myocardial infarction is well established and it is also known i that necrosis or damage of the liver tissue causes increase of the serum transaminase. Not only heart muscle or liver tissue, but skeletal muscle, brain or kidney tissue produce serum transaminase significantly.
A clinical evaluation was made here in determination of serum glutamic oxalacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGP-T) on 42 patients with various liver diseases and 5 healthy men. Along with SGO-T and SGP-T, following liver function studies were also done: serum bilirubin, cephalin flocculation, serum cholesterol, serum protein with AJG ratio, bromsulfalein test and alkaline phosphatase.
The control group showed normal value of SGO-T and SGP-T, and most of clonorchiasis patients showed also normal value. Infectious hepatitis showed the highest value in both SGO-T and SGP-T and most of ´s other Iiver patients showed also elevation of SGO-T and SGP-T.
It was observed that the increase of the serum transaminase value was parallel with the hepatic damage and the value of the serum transaminase seems to be more sensitive than the other liver function tests, and it seems to be significant in evaluation of the liver disease.
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KEYWORD
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